@article{gowri2013relationship,
  title = {Relationship of High Sensitivity C-Reactive Protein and Other Biochemical Parameters of Metabolic Syndrome in Women with Polycystic Ovarian Syndrome and BMI Matched Controls},
  author = {Vaidyanathan Gowri and Gauhar Rizvi and Shabnam Saquib},
  year = 2013,
  url = {https://ibimapublishing.com/articles/ENDO/2013/503467/},
  journal = {Research in Endocrinology},
  volume = 2013 (2013),
  pages = 6,
  doi = 10.5171/2013.503467,
  abstract = {Background: Polycystic ovarian syndrome (PCOS) is characterized by hyperandrogenism, chronic anovulation and infertility. In addition to reproductive abnormalities, a significant proportion of women suffer from obesity, insulin resistance and other features of metabolic syndrome. Metabolic complications associated with insulin resistance are increased in PCOS independent of obesity including an adverse cardiovascular risk profile. Methods: High sensitivity CRP (hs CRP) was measured in 60 PCOS women and 60 age and BMI matched controls with regular menstruation. Other biochemical parameters like fasting blood glucose (FBS), lipid profile (Low density lipoprotein-(LDL), high density lipoprotein (HDL) and triglycerides (TG)) were measured in a subset of 18 PCOs women and age and BMI matched controls. Results: A significant positive relationship was observed between BMI & hs CRP (P < .001); the degree of relationship was stronger among PCOS cases than controls.  Relationship of hs-CRP and FBS was stronger among cases (P < .001) than controls (P =0.03) A significant relationship was observed between LDL and hs-CRP among cases (P .001) and inverse but insignificant (p=0.110) relationship was found among controls.  Conclusion: Though hs-CRP significantly correlated with obesity, other biochemical parameters like fasting blood glucose and LDL correlated with hs CRP significantly in PCOS women.},
  keywords = {C- reactive protein, Controls, Metabolic syndrome, Obesity, Polycystic Ovarian syndrome (PCOS)},
  note = Article ID: 503467
}