@article{taar2014perforation,
  title = {Perforation of Ileum Due to Thrombosis in the Course of Paroxysmal Nocturnal Hemoglobinuria: A Case Report},
  author = {Pinar Tosun Taşar and Sevnaz Sahin and Asu Fergun Yilmaz and Ceyda Tunakan Dalgic and Emine Nihal Mete Gokmen and Fehmi Akcicek and Guray Saydam and Fahri Sahin},
  year = 2014,
  url = {https://ibimapublishing.com/articles/IJCRM/2014/504318/},
  journal = {International Journal of Case Reports in Medicine},
  volume = 2014 (2014),
  pages = 4,
  doi = 10.5171/2014.504318,
  abstract = {Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease which is characterized by hemolysis, thromboses in unexpected sites and multi-organ involvement. Arterial thromboses could result in necrosis and dysfunction of involved organs. In some cases, organ dysfunctions could be fatal as in involvement of heart, small intestine and lung. Eculizumab is a monoclonal antibody which decreases risk of thrombosis and hemolysis in patients with PNH by inhibiting complement system. Hereby, we present a case with acute abdomen which was operated and small intestinal necrosis was detected due to thromboses which was resulted in PNH undiagnosed until the time of operation. Unexpected thromboses should be carefully investigated in terms of potential coexistence of PNH associated with multi-organ involvement and treated appropriately.},
  keywords = {Paroxysmal nocturnal hemoglobinuria (PNH), thrombosis, eculizumab.},
  note = Article ID: 504318
}