@article{dutta2012demographic,
  title = {Demographic and Clinical Features of Patients with Dengue in Northeastern Region of India: A Retrospective Cross-Sectional Study during 2009-2011},
  author = {Prafulla Dutta and Siraj A. Khan and Jani Borah and Jagadish Mahanta},
  year = 2012,
  url = {https://ibimapublishing.com/articles/JVM/2012/786298/},
  journal = {Journal of Virology and Microbiology},
  volume = 2012 (2012),
  pages = 11,
  doi = 10.5171/2012.786298,
  abstract = {The incidence of fever cases of unknown origin has increased in Northeastern Region of India in recent years. We conducted passive surveillance and performed laboratory testing on suspected cases for the presence of dengue infection during 2009—2011. We estimated the incidence by applying age, sex and season adjusted dengue positivity. We identified 430 suspected cases of which 143 (33.3%) were found to be laboratory-confirmed dengue cases. Dengue transmission was found to occur in post-monsoon season (September-December). We evaluated the differences of clinical features and hematologic abnormalities that occurred in laboratory dengue positive and negative cases. Significantly higher percentage of dengue patients had headache, eye pain and vomiting (P < 0.05). Diarrhoea as well as abdominal pain was observed more commonly in laboratory dengue negative patients but the difference was not significant (P > 0.05). Thrombocytopenia was observed in significantly higher percentage of positive patients (P < 0.001) with significantly lower platelets counts (P < 0.001). The elevated level of Aspartate transaminase (P < 0.001) and Alanine transaminase (P = 0.002) was also significantly higher side in positive patients. This study provides some important information in clinical and laboratory data that can be used for early diagnosis and subsequently for appropriate treatment of dengue infections. Thus, the passive surveillance and laboratory confirmation provides a better estimate of the actual dengue disease burden and a scope to further refine dengue prevention strategies.},
  keywords = {Dengue, Northeast India, Clinical features, Passive surveillance.},
  note = Article ID: 786298
}