@article{teparatburana2015efficacy,
  title = {The Efficacy of Subgingivally Delivered Andrographis Paniculata Gel to Treat Patients with Periodontitis},
  author = {Thitiwan Teparat-Burana and Chalita Samarnsotthiwong and Julalux Kasetsuwan and Mullika Sirirat and Pleumchitt Rojanapanthu},
  year = 2015,
  url = {https://ibimapublishing.com/articles/DENT/2015/786773/},
  journal = {Journal of Research and Practice in Dentistry},
  volume = 2015 (2015),
  pages = 14,
  doi = 10.5171/2015.786773,
  abstract = {This study compared the clinical effects of scaling and root planing (SRP) after the adjunctive subgingival administration of Andrographis paniculata (AP) gel or placebo (PB) gel in a 6-month clinical trial for patients with chronic periodontitis. The study was a split-mouth, single-blind, randomized and controlled clinical trial that compared two treatment modalities (SRP+PB and SRP+AP) in single-rooted teeth with a probing depth (PD) of 5 mm or more. The clinical parameters, including PD, clinical attachment level (CAL), plaque index (PI), gingival index (GI), bleeding on probing (BOP), and radiographic examinations were recorded at baseline, 3 months and 6 months. The results showed that both treatment groups significantly improved with regard to clinical parameters (p<0.05); however, the between-group differences were mostly insignificant (p>0.05), although SRP+AP showed a greater PD reduction than SRP+PB (p<0.05) between baseline and 3 months. In conclusion, the adjunctive use of AP gel significantly reduces PD and significantly improves attachment level.},
  keywords = {Andrographis paniculata gel, chronic periodontitis, non-surgical therapy},
  note = Article ID: 786773
}