@article{simmons2014investigation,
  title = {Investigation of the Glycaemic Profile of Corticosteroid-Induced Diabetes following Renal Transplant using Continuous Glucose Monitoring},
  author = {Lisa R. Simmons and Lynday Molyneaux and Elizabeth L Chua and Steve Chadban and Dennis K. Yue},
  year = 2014,
  url = {https://ibimapublishing.com/articles/DIAB/2014/886759/},
  journal = {Journal of Research in Diabetes},
  volume = (2014),
  pages = 13,
  doi = 10.5171/2014.886759,
  abstract = {The aim of this study was to use continuous glucose monitoring (CGM) to evaluate the timing and magnitude of glucose excursions in renal transplant recipients receiving oral prednisone, which may assist in determining optimal time for detection of hyperglycaemia and treatment strategies for this group of patients Ten patients underwent CGM at 3-10 weeks post-kidney transplantation. CGM was undertaken for 3 consecutive days and area under the curve (GAUC) was calculated for morning, afternoon and evening and compared to night. Multivariate analysis was used to determine factors associated with hyperglycaemia. Hyperglycaemia was most severe in the afternoon period. The presence of established diabetes was a significant determinant of the magnitude of rise in GAUC in the Morning and Afternoon Periods (p<0.002). Night-time hyperglycaemia was predictive of high GAUC at all other time periods. Kidney transplant recipients taking prednisone, a calcineurin inhibitor and mycophenolate exhibited a maximal increase in blood glucose during the afternoon. BGL measurement in the afternoon is likely to be more sensitive than fasting BGL in detecting hyperglycaemia and guiding the need and timing for antihyperglycaemic therapy. By contrast, measurement of fasting BGL alone, an inadequate measure.},
  keywords = {corticosteroids, diabetes, transplantation, continuous glucose monitoring},
  note = Article ID: 886759
}