Pyruvate Kinase Deficiency along with Detection of Plasminogen Activator Inhibitor (PAI-1) 4G/4G Homozygous Genotype in Pregnancy
Obstetrics & Gynecology: An International Journal
The most frequent enzyme abnormality of the glycolytic pathway which causes hereditary non-spherocytic hemolytic anemia is red cell pyruvate kinase (PK) deficiency.The disease is transmitted as an autosomal recessive trait. The case of a successful pregnancy in a 38 year- old woman with Pyruvate Kinase…