Severe Toxicity of Clofarabine combined to Cyclophosphamide and Etoposide in two Children with Relapsed Acute Lymphoblastic Leukaemia (ALL)
International Journal of Case Reports in Medicine
Clofarabine use has been reported to be safe in previous studies. We report 2 cases of relapsed ALL in children, one of them occurring after bone marrow transplantation. The patients were treated with clofarabine 40 mg/m², etoposide 100 mg/m² and cyclophosphamide 440 g/m². They developed…