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UDP glucuronosyltransferases (UGTs) are a family of enzymes that glucuronidate a variety of exogenous and endogenous compounds, including androgens; which makes them more hydrophilic, changes biological activity, and aids biological excretion. UGT2B17 has been identified as the major enzyme for testosterone glucuronidation, where UGT2B15 has…

Background: Glutathione S-transferases (GSTs) are members of the phase II biotransformation enzymes that play a key role in cellular detoxification of chemical carcinogens and xenobiotics. Variations at GST genes have been reported in different human populations, and some association studies have reported increased risk for…

Business clusters consist of economic structures assuring the often tenuous link between research regarding efficient national industrial policies, and regional planning and territorial anchoring issues. From this perspective, the logic of a synergy pertinent to global and local issues remains to be created around a…

Tuberculosis is an infectious diseases of animals which causes heavy economic losses in livestock. A total of 17601 animals including 9021cattle and 8580 buffalo were screened for tuberculosis at five government and fifty private livestock farms in Punjab, Pakistan from 2006 to 2010. Out of…

There is a growing interest in cloud computing due to its various benefits such as the efficient utilization of computing resources. However, privacy and security concerns are among the main obstacles facing the widespread adoption of this new technology. For instance, it is more desirable…

In the field of project management, rapidly changing environments are newly recognized and of increased challenge. Old-fashioned inflexible methods, focused around process control, are considered obsolete. Along with the increasing diffusion of project management worldwide, a comprehensive governance principle does not yet address this objective.…

Cancer patients experience distress during their disease that likely will be exacerbated at some point by pain. Poor pain control is common among those with cancer, and the primary medical treatment is the prescription of opioid medications. The purpose here was to investigate the efficacy…

Since mesenchymal lesions (bone and soft tissue) are heterozygous and classified on histogenetic basis, it is difficult to cytologically categorize and subtype them into specific entities. Nevertheless, the necessity for determining at least the general category of these neoplasms as benign or malignant arises since,…

The laser plays a significant role in the lung parenchyma sparing resection for pulmonary neoplasms. The high performance Nd: YAG laser system emitting the 1318 nm wavelength exclusively up to a power of 120 W was used, consisting of the thin flexible quartz fibres (400…

Alkaline phosphatase (ALP) is known to be expressed in the several somatic stem cells and cancer cells. To investigate whether ALP may be a promising marker for cancer stem cells (CSCs), we examined the expression of ALP in human squamous cell carcinoma HeLa cells using…