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Imbalances in the corticosteroid millieu have been implicated in several neuropsychiatric disorders and neuronal damage. Administration of the high therapeutic doses of the glucocorticoids also induces neuronal damage. We investigated the early electrophysiological manifestations of neurotoxic action of the glucocorticoids. Administration of the toxic doses…

Mice injected with multiple low dose of streptozotocin (mld-SZ) or transferred with  mononuclear splenocytes (MS) from mld-SZ  donors constitute animal models that allow the study of  autoimmune diabetes. Mld-SZ mice show a progressive beta-cell destruction iniciated during non-specific islet inflammation involving free radicals as nitric…

The tendency of repeating history has made any financial crisis a valuable source to be explored and studied. It will make people be more prepared and ready to anticipate. This paper examined the nature of linkages between exchange rate and macroeconomic fundamentals over 1997-2004. It…

The purpose of the present work is twofold. On a first stage, it aims at highlighting the corruption-related issues in terms of its definitions and different perceptions with respect to some economic theories, while stressing the specific factors lying behind the spread of such practice…

The rarely investigated themes on the indigenous economic’s influence on small business development have made the local governments’ policies on regional development merely relied on large industries as the main engine. The paper aims to examine the effects of local culture, government role, and entrepreneurial…

Knowledge organisation is critical to ensure that knowledge is being distributed widely in an organisation. There are a lot of approaches to organise and manage knowledge. One approach that has been found for so long but has not been explored to its optimum is taxonomy…

The background of this article is to evaluate Health-Related Quality of Life (HRQoL) of patients with diabetes mellitus living in the community and to assess associated factors. A cross-sectional survey through telephone interviews was performed on a sample of patients diagnosed with diabetes mellitus, randomly…

The background of this article is to retrospectively investigate the role of B-type natriuretic peptide (BNP) levels as an independent prognostic marker for mortality in diabetic patients with foot ulcer. In the period 1 January-30 June 2009, 279 diabetic patients were admitted to our foot center…

Background: Individuals with type 2 diabetes mellitus (T2DM) have high prevalence of liver diseases due to underlying insulin resistance. Deranged lipoprotein metabolism in insulin resistant state also result in hepatic cell injury. Present study evaluated serum Alanine Transaminases (ALT) and lipid profile in diagnosed cases…

Apoptosis is considered as a tightly regulated active process signified by specific morphological and biochemical. On contrary to apoptosis, necrosis is a passive, energy independent pathologic process. The significance of understanding the apoptosis cascade mechanism is imperative as apoptosis being component of both physiological and…